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  2. Ursodoxicoltaurine - Wikipedia

    en.wikipedia.org/wiki/Ursodoxicoltaurine

    Ursodoxicoltaurine is the international nonproprietary name (INN) for the pharmaceutical form of tauroursodeoxycholic acid (TUDCA). It is also known as taurursodiol . Tauroursodeoxycholic acid is a naturally occurring hydrophilic bile acid which is the taurine conjugated form of ursodeoxycholic acid (UDCA).

  3. Ursodeoxycholic acid - Wikipedia

    en.wikipedia.org/wiki/Ursodeoxycholic_acid

    Ursodeoxycholic acid has been shown to exert anti-inflammatory and protective effects in human epithelial cells of the gastrointestinal tract. It has been linked to regulation of immunoregulatory responses by regulation of cytokines , [ 35 ] antimicrobial peptides defensins , [ 36 ] and take an active part in increased restitution of wound in ...

  4. Specialized pro-resolving mediators - Wikipedia

    en.wikipedia.org/wiki/Specialized_pro-resolving...

    The production and activities of the SPM suggest a new view of inflammation wherein the initial response to foreign organisms, tissue injury, or other insults involves numerous soluble cell signaling molecules that not only recruit various cell types to promote inflammation but concurrently cause these cells to produce SPM which feed back on their parent and other cells to dampen their pro ...

  5. Damage-associated molecular pattern - Wikipedia

    en.wikipedia.org/wiki/Damage-associated...

    Once a DAMP is released from the cell, it promotes a noninfectious inflammatory response by binding to a pattern recognition receptor (PRR). [4] Inflammation is a key aspect of the innate immune response; it is used to help mitigate future damage to the organism by removing harmful invaders from the affected area and start the healing process. [5]

  6. Inflammatory cytokine - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_cytokine

    An inflammatory cytokine or proinflammatory cytokine is a type of signaling molecule (a cytokine) that is secreted from immune cells like helper T cells (T h) and macrophages, and certain other cell types that promote inflammation.

  7. Systemic inflammation - Wikipedia

    en.wikipedia.org/wiki/Systemic_inflammation

    Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...