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  2. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    The lesion evolution under MRI has been reported to begin as a pattern of central hyperintensity. This was seen in the majority of new lesions, both on proton density and contrast-enhanced T1-weighted images. [98] When gadolinium is used, the lesion expansion can be classified as nodular or ringlike. [99]

  3. Radiologically isolated syndrome - Wikipedia

    en.wikipedia.org/wiki/Radiologically_isolated...

    The nerve lesions in these people show dissemination in space with an otherwise normal neurological examination and without historical accounts of typical MS symptoms. [ 1 ] MRI findings that are consistent with multiple sclerosis have been observed in healthy people who underwent MRI scanning, and 50% go on to develop symptomatic MS, sometimes ...

  4. Tumefactive multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Tumefactive_multiple_sclerosis

    Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics for those of standard multiple sclerosis (MS). It is called tumefactive as the lesions are "tumor-like" and they mimic tumors clinically, radiologically and sometimes pathologically.

  5. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis. Multiple sclerosis is an autoimmune disease, primarily mediated by T-cells. [15] The three main characteristics of MS are the formation of lesions in the central nervous system (also called plaques), inflammation, and the destruction of myelin sheaths of neurons.

  6. Pathophysiology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Multiple sclerosis differs from other idiopathic inflammatory demyelinating diseases in its confluent subpial cortical lesions. These types of lesions are the most specific finding for MS, being exclusively present in MS patients, though currently they can only be detected at autopsy.

  7. Lesional demyelinations of the central nervous system

    en.wikipedia.org/wiki/Lesional_demyelinations_of...

    Marburg multiple sclerosis, an aggressive form, also known as malignant, fulminant or acute MS. Tumefactive Multiple sclerosis: lesions whose size is more than 2 cm, with mass effect, oedema and/or ring enhancement [9] [10] AntiMOG associated encephalomyelitis: Lesions similar to ADEM sometimes and to NMO some others. It is not normal, but can ...

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