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Nail abnormalities in ED often manifest as dysplastic or poorly formed nails. Affected individuals may have thin, brittle, or ridged nails that are prone to splitting and breaking. In severe cases, nails may be entirely absent or exhibit atypical growth patterns, including spoon-like (koilonychia) or thickened (pachyonychia) appearances. [1] [2]
The hair is often light-coloured, brittle, and slow-growing. This condition is also characterized by absent teeth or teeth that are malformed. Hypohidrotic ectodermal dysplasia is the most common form of ectodermal dysplasia in humans. It is estimated to affect at least 1 in 17,000 people worldwide. [citation needed]
Symptoms include brittle hair, mild mental retardation and nail dysplasia.The syndrome was first observed in Sabinas, a small community in northern Mexico.. The principal biochemical features of the illness are reduced hair cystine levels, increased copper/zinc ratio, and presence of arginosuccinic acid in the blood and urine.
Hormones and certain medications can also make pigmented bands in the nails, but be especially watchful for nail cancer symptoms, such as a brown or dark stripe that goes from the cuticle out to ...
Brown nails can indicate a thyroid disease or malnutrition; white nails can point to an iron deficiency; and strangest of all, nails with a bluish-gray tint can mean that your body might not be ...
IBIDS syndrome, following the acronym from ichthyosis, brittle hair and nails, intellectual impairment and short stature, is the Tay syndrome or sulfur-deficient brittle hair syndrome, first described by Tay in 1971. [9] (Chong Hai Tay was the Singaporean doctor who was the first doctor in South East Asia to have a disease named after him.