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The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression.Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomonic Koplik spot seen on buccal mucosa opposite to lower 1st and 2nd molars.
An electron micrograph of the measles virus. Measles is caused by the measles virus, a single-stranded, negative-sense, enveloped RNA virus of the genus Morbillivirus within the family Paramyxoviridae. [51] The virus is highly contagious and is spread by coughing and sneezing via close personal contact or direct contact with secretions. [52 ...
Viral pathogenesis is the study of the process and mechanisms by which viruses cause diseases in their target hosts, often at the cellular or molecular level. It is a specialized field of study in virology. [1] Pathogenesis is a qualitative description of the process by which an initial infection causes disease. [2]
SSPE is a rare condition, although there is still relatively high incidence in Asia and the Middle East. However, the number of reported cases is declining since the introduction of the measles vaccine. Eradication of the measles virus prevents the SSPE mutation and therefore the progression of the disease, or even the initial infection itself.
Diseases in humans associated with viruses classified in this genus include measles; in animals, they include acute febrile respiratory tract infection and Canine distemper. [3] In 2013, a wave of increased death among the Common bottlenose dolphin population was attributed to morbillivirus.
Koplik's spots (also Koplik's sign) are a prodromic viral enanthem of measles manifesting two to three days before the measles rash itself. They are characterized as clustered, white lesions on the buccal mucosa (opposite the upper 1st & 2nd molars ) and are pathognomonic for measles . [ 2 ]
Alright—so a quick review of measles: measles is an airborne pathogen that’s highly contagious, and causes cough, conjunctivitis, and coryza, as well as complications like pneumonia and encephalitis, and can be prevented through vaccination. [1] Image 17 of measles video
Measles virus, another negative-stranded RNA virus, was another research focus. [5] [6] Measles is usually an acute infection but rarely viral persistence in the nervous system can eventually lead to subacute sclerosing panencephalitis. Oldstone postulated that changes in viral products induced by the antibody response, termed "antibody-induced ...