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Hair-based drug tests are the most accurate, as the chart below shows, since traces of everything from alcohol to morphine can remain in the follicle for up to 90 days: bi_graphics_how long drugs ...
{{Infobox drug}} articles that have Physiological parameters input: <!-- Physiology --> | source_tissues = | target_tissues = | receptors = | agonists = | antagonists = | precursor = | biosynthesis = Note: |metabolism= will only show in the Physiologic data section when other input is present. Same for metabolism input under the pharmacokinetic ...
The body's posture changes as the pregnancy progresses. The pelvis tilts and the back arches to help keep balance. Poor posture occurs naturally from the stretching of the woman's abdominal muscles as the fetus grows. These muscles are less able to contract and keep the lower back in proper alignment. The pregnant woman has a different pattern ...
The action of drugs on the human body (or any other organism's body) is called pharmacodynamics, and the body's response to drugs is called pharmacokinetics. The drugs that enter an individual tend to stimulate certain receptors, ion channels, act on enzymes or transport proteins. As a result, they cause the human body to react in a specific way.
Most of the time these postnatal changes are normal and can be managed with medication and comfort measures, but in a few situations complications may develop. [1] Postpartum physiological changes may be different for women delivering by cesarean section. [2]
Therefore, the chemical characteristics of a drug will determine its distribution within an organism. For example, a liposoluble drug will tend to accumulate in body fat and water-soluble drugs will tend to accumulate in extracellular fluids. The volume of distribution (V D) of a drug is a property that quantifies the extent of its distribution ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
The V D is not a physiological value; it is more a reflection of how a drug will distribute throughout the body depending on several physicochemical properties, e.g. solubility, charge, size, etc. The unit for Volume of Distribution is typically reported in litres. As body composition changes with age, V D decreases.