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Chickenpox, also known as varicella (/ ˌ v ɛ r ə ˈ s ɛ l ə / VER-ə-SEL-ə), is a highly contagious disease caused by varicella zoster virus (VZV), a member of the herpesvirus family. [ 3 ] [ 7 ] [ 5 ] The disease results in a characteristic skin rash that forms small, itchy blisters , which eventually scab over. [ 1 ]
Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
The vaccinia virus is an effective tool for foreign protein expression, as it elicits a strong host immune-response. The vaccinia virus enters cells primarily by cell fusion, although currently the receptor responsible is unknown. [citation needed] Vaccinia contains three classes of genes: early, intermediate and late.
Smallpox (variola orthopox virus ) Early Rash vs chickenpox.gif; Human body silhouette.svg; Author: Smallpox (variola orthopox virus ) Early Rash vs chickenpox.gif: Unknown author; Human body silhouette.svg: *Upper body front.png: Mikael Häggström; Background made transparent by Frédéric MICHEL; for Graphic Lab (fr). derivative work: RexxS
Other classifications are determined by the disease caused by the virus or its morphology, neither of which are satisfactory due to different viruses either causing the same disease or looking very similar. In addition, viral structures are often difficult to determine under the microscope.
[1] [2] The most widely known member of the genus is Variola virus, which causes smallpox. It was eradicated globally by 1977, through the use of Vaccinia virus as a vaccine. The most recently described species is the Borealpox virus, first isolated in 2015. [3]
Chikungunya virus is an alphavirus transmitted by Aedes mosquitoes. The disease can cause severe joint pain, sometimes lasting for several months. Outbreaks have occurred across Africa, Asia and India, and in 2013–14, in South America and the Caribbean. Credit: A2-33 (8 December 2013) Portal:Viruses/Selected picture/25
Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and glandular fever. Herpesvirales is the sole order in the class Herviviricetes, which is the sole class in the phylum Peploviricota.