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  2. Azithromycin - Wikipedia

    en.wikipedia.org/wiki/Azithromycin

    Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to peak concentration (T max) in adults is 2.1 to 3.2 hours for oral dosage forms.

  3. Antibiotic synergy - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_synergy

    Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient level, the boosted antimicrobial potency provided by synergy allows the body to more rapidly clear infections, resulting in shorter courses of antibiotic therapy. [3] Shorter courses of therapy in turn reduce the effects of dose-related toxicity, if applicable ...

  4. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Azithromycin: Zithromax, Sumamed, Xithrone: Streptococcal infections, syphilis, upper respiratory tract infections, lower respiratory tract infections, mycoplasmal infections, Lyme disease: Nausea, vomiting, and diarrhea (especially at higher doses) Prolonged cardiac QT interval (especially erythromycin) Hearing loss (especially at higher doses ...

  5. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The indicator DDDs per inhabitant per year can be used for drugs normally prescribed for short treatment duration (e.g., antibiotics) to indicate the average number of days in a year a person may take that treatment. The extent to which estimates using DDD reflect actual clinical practice depends on how close the DDD is to the typical ...

  6. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug. [3] AUC becomes useful for knowing the average concentration over a time interval, AUC/t.

  7. Trough level - Wikipedia

    en.wikipedia.org/wiki/Trough_level

    In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is ...

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