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The disease is characterised by inflammatory changes in the moisture-producing glands throughout the body, leading to reduced secretions from glands that produce saliva, tears and other secretions throughout the body. [8] Primary Sjögren's syndrome is the combination of dry eyes and xerostomia.
Conditions that can cause saliva overproduction include: [4] Rabies; Pellagra (niacin or vitamin B 3 deficiency) [6] Gastroesophageal reflux disease, in such cases specifically called a water brash (a loosely defined lay term), and is characterized by a sour fluid or almost tasteless saliva in the mouth [7]
For example, Basaglar, Abasaglar, and Abasria all refer to the same brand. Abasria is the brand's former name, [9] while Basaglar and Abasaglar are regional. [9] [10] [11] The three companies which produce the most insulin are Lilly, Novo Nordisk and Sanofi. These three corporations control 99% of the global market by value and 96% by volume. [12]
Pilocarpine is a cholinergic drug, meaning it has the same effects as the neurotransmitter acetylcholine. Acetylcholine has the function of stimulating the salivary glands to actively produce saliva. [41] The increase in saliva flow is effective in improving the movement of tastants to the taste buds. [39]
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Risk factors include conditions that result in less saliva, such as diabetes mellitus, Sjögren syndrome and some medications. [4] Medications that decrease saliva production include antihistamines and antidepressants. [4]
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