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Image showing Gastrointestinal Stromal Tumor after surgical removal. For localized, resectable adult GISTs, if anatomically and physiologically feasible, surgery is the primary treatment of choice. [22]: 69 Surgery can be potentially curative, but watchful waiting may be considered in small tumors in carefully selected situations. [28]
The prognosis for these types of tumors depends heavily on the size of the tumor and the rate of mitosis, however approximately 60 percent of GISTs are diagnosed as benign. [4] Surgery to remove the tumor is the primary treatment method, although imatinib, everolimus, and rapamycin may soon be approved as alternative treatment and management ...
The most definitive method of cancer diagnosis is through open surgical biopsy. [109] Most stomach tumors are malignant with evidence of spread to lymph nodes or liver, making treatment difficult. Except for lymphoma, surgery is the most frequent treatment option for stomach cancers but it is associated with significant risks. [citation needed]
Pancreatic cancer has a poor prognosis, [2] with a five-year survival rate of less than 5%. By the time the cancer is diagnosed, it is usually at an advanced, inoperable stage. [9] Only one in about fifteen to twenty patients is curative surgery attempted. [11] Pancreatic cancer tends to be aggressive, and it resists radiotherapy and ...
Duodenal cancer has more in common with stomach cancer, while cancer of the jejunum and ileum have more in common with colorectal cancer. Five-year survival rates are 65%. [3] Experts [which?] believe that small intestine cancer develops much like colorectal cancer. It first begins as a small growth on the inner lining of the intestine (polyp ...
The tumor-induced stromal change hypothesis claims that tumor cells can dedifferentiate into fibroblasts and, themselves, secrete more collagen. [3] This was observed in desmoplastic melanoma, in which the tumor cells are phenotypically fibroblastic and positively express genes associated with ECM production. [ 13 ]
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