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It is unclear if phytoestrogens have any effect on the cause or prevention of cancer in women. [ 1 ] [ 36 ] Some epidemiological studies have suggested a protective effect against breast cancer. [ 1 ] [ 36 ] [ 37 ] Additionally, other epidemiological studies found that consumption of soy estrogens is safe for patients with breast cancer, and ...
Phytoestrogens are chemicals which act like the hormone estrogen. Estrogen is important for women's bone and heart health, but high amounts of it has been linked to breast cancer. [18] In the plant, the phytoestrogens are involved in the defense system against fungi. [19] Phytoestrogens can do two different things in a human body.
Genistein was found to increase the rate of proliferation of estrogen-dependent breast cancer when not cotreated with an estrogen antagonist. [ 51 ] [ 52 ] [ 53 ] It was also found to decrease efficiency of tamoxifen and letrozole - drugs commonly used in breast cancer therapy.
The American Cancer Society reports 5-year relative survival rates of over 70% for women with stage 0-III breast cancer with a 5-year relative survival rate close to 100% for women with stage 0 or stage I breast cancer. The 5-year relative survival rate drops to 22% for women with stage IV breast cancer. [3]
The trial included 325 patients from across 28 countries.
8-Prenylnaringenin (8-PN; also known as flavaprenin, (S)-8-dimethylallylnaringenin, hopein, or sophoraflavanone B) is a prenylflavonoid phytoestrogen. It is reported to be the most estrogenic phytoestrogen known. [1] The compound is equipotent at the two forms of estrogen receptors, ERα and ERβ, [2] and it acts as a full agonist of ERα. [3]
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