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Treatment of excessive daytime sleepiness (EDS) relies on identifying and treating the underlying disorder which may cure the person from the EDS. Drugs like modafinil , [ 22 ] armodafinil , [ 23 ] pitolisant [ 24 ] (Wakix), sodium oxybate (Xyrem) oral solution, have been approved as treatment for EDS symptoms in the United States.
The main treatment of excessive daytime sleepiness is done through central nervous system stimulants. Methylphenidate and dextroamphetamine are most used stimulants to controlled EDS. Increased dopamine release is felt to be the main property explaining wake-promotion from these medications. [20]
Pitolisant is indicated in adults for the treatment of narcolepsy. [3] [4] Narcolepsy is a chronic sleep disorder that causes overwhelming daytime drowsiness. [4] Pitolisant is also indicated to improve alertness and reduce excessive daytime sleepiness in adults with obstructive sleep apnea. [5] [12]
In contrast, the sleep issues studied here include excessive daytime sleepiness (falling asleep during meals or social activities) and a marked lack of enthusiasm for daily tasks,” Dr. Porter said.
Excessive sweating. Headaches. Insomnia. Nausea. Vomiting. ... (a sleep disorder that causes excessive daytime tiredness or the sudden need to sleep). ... Medication isn’t a one-size-fits-all ...
Chronic kidney disease is commonly associated with sleep symptoms and excessive daytime sleepiness. 80% of those on dialysis have sleep disturbances. Sleep apnea can occur 10 times as often in uremic patients than in the general population and can affect up to 30-80% of patients on dialysis, though nighttime dialysis can improve this.
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