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The term "homology" was first used in biology by the anatomist Richard Owen in 1843 when studying the similarities of vertebrate fins and limbs, defining it as the "same organ in different animals under every variety of form and function", [6] and contrasting it with the matching term "analogy" which he used to describe different structures ...
"The molecular weight of Sulculus myoglobin is 41kD, 2.5 times larger than other myoglobins." Moreover, its amino acid sequence has no homology with other invertebrate myoglobins or with hemoglobins, but is 35% homologous with human indoleamine dioxygenase (IDO), a vertebrate tryptophan-degrading enzyme. It does not share similar function with IDO.
Convergent evolution is the independent evolution of similar features in species of different periods or epochs in time. Convergent evolution creates analogous structures that have similar form or function but were not present in the last common ancestor of those groups.
Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal (or lateral) gene ...
Homology is the term used to characterize the similarity of features that can be parsimoniously explained by common ancestry. Homoplasy is the term used to describe a feature that has been gained or lost independently in separate lineages over the course of evolution.
A protein superfamily is the largest grouping of proteins for which common ancestry can be inferred (see homology).Usually this common ancestry is inferred from structural alignment [1] and mechanistic similarity, even if no sequence similarity is evident. [2]
In mathematics, the term homology, originally introduced in algebraic topology, has three primary, closely-related usages.The most direct usage of the term is to take the homology of a chain complex, resulting in a sequence of abelian groups called homology groups.
Homology model of the DHRS7B protein created with Swiss-model and rendered with PyMOL. Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "target" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "template").