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Sertraline for Depression & Anxiety: Breaking Down the Side Effects ... researchers concluded that antidepressants may contribute to a long-term increased risk of weight gain. ... These Zoloft ...
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).
Higher dosage does, however, increase the incidence and severity of adverse events associated with excessive 5-HT re-uptake inhibition. [6] Figure 2 Inhibition of re-uptake transport proteins, e.g. SERT, results in increased concentration of neurotransmitters, e.g. 5-HT, in the synaptic cleft, leading to improvement of depression symptoms
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram ...
Increased reactivity. ... Post-traumatic stress disorder can also coexist with anxiety disorders, ... (Zoloft) and paroxetine (Paxil), are FDA-approved to treat PTSD.
In some people, this state change can increase suicidal tendencies, especially in those under age 25 and during the initial weeks of treatment. [2] SSRI-induced activation syndrome is well-accepted by clinicians. [3] It is unclear whether jitteriness/anxiety syndrome predicts either good or poor prognosis (level D). [4]
But as the first-line treatment for mental health conditions like depression and anxiety, ... increased levels of serotonin are thought to affect testosterone and dopamine. ... (Zoloft) Fluoxetine ...