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Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. [1] The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they produce will fill the abdominal cavity.
Appendix cancer, also known as appendiceal cancer, is a very rare malignant tumor that forms in the vermiform appendix. [7] Gastrointestinal stromal tumors are rare tumors with malignant potential. [8] Primary lymphomas can occur in the appendix. Breast cancer, colon cancer, and tumors of the female genital tract may metastasize to the appendix ...
A mucinous neoplasm (also called colloid neoplasm) is an abnormal and excessive growth of tissue with associated mucin (a fluid that sometimes resembles thyroid colloid). It arises from epithelial cells that line certain internal organs and skin, and produce mucin (the main component of mucus ).
A more common cause of pseudomyxoma peritonei is a mucin-producing tumor of the appendix. Since mucinous tumors arising from the ovary usually only involve one ovary, the presence of involvement in both ovaries with a mucinous tumor suggests that the tumor may have arisen in another location, and further study is warranted.
Prognosis and treatment is the same as for the most common type of ovarian cancer, which is epithelial ovarian cancer. [6] [7] The median survival of primary peritoneal carcinomas is usually shorter by 2–6 months time when compared with serous ovarian cancer. Studies show median survival varies between 11.3 and 17.8 months.
Peritoneal implants are very uncommon (15%), and when they occur, a mixed histology as well as the presence of pseudomyxoma peritonei must be ruled out. These are considered a differentiated entity, in which peritoneal involvement of a mucinous carcinoma is primarily of digestive origin, generally of the appendix. [4]
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Cystadenocarcinoma is a malignant form of a cystadenoma and is a cancer derived from glandular epithelium, in which cystic accumulations of retained secretions are formed.. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases oc