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  2. Mass spectrometry - Wikipedia

    en.wikipedia.org/wiki/Mass_spectrometry

    Mass spectrometry data analysis is specific to the type of experiment producing the data. General subdivisions of data are fundamental to understanding any data. Many mass spectrometers work in either negative ion mode or positive ion mode. It is very important to know whether the observed ions are negatively or positively charged.

  3. Ion source - Wikipedia

    en.wikipedia.org/wiki/Ion_source

    The mass/charge ratios of these secondary ions are measured with a mass spectrometer to determine the elemental, isotopic, or molecular composition of the surface to a depth of 1 to 2 nm. In a liquid metal ion source (LMIS), a metal (typically gallium ) is heated to the liquid state and provided at the end of a capillary or a needle.

  4. Electrospray ionization - Wikipedia

    en.wikipedia.org/wiki/Electrospray_ionization

    Electrospray ionization is the ion source of choice to couple liquid chromatography with mass spectrometry (LC-MS). The analysis can be performed online, by feeding the liquid eluting from the LC column directly to an electrospray, or offline, by collecting fractions to be later analyzed in a classical nanoelectrospray-mass spectrometry setup.

  5. Electron ionization - Wikipedia

    en.wikipedia.org/wiki/Electron_ionization

    It was the first modern mass spectrometer and used positive rays to determine the ratio of the mass to charge of various constituents. [6] In this method, the ion source used an electron beam directed at a solid surface. The anode was made cylindrical in shape using the metal which was to be studied. Subsequently, it was heated by a concentric ...

  6. Direct analysis in real time - Wikipedia

    en.wikipedia.org/wiki/Direct_analysis_in_real_time

    In mass spectrometry, direct analysis in real time (DART) is an ion source that produces electronically or vibronically excited-state species from gases such as helium, argon, or nitrogen that ionize atmospheric molecules or dopant molecules. The ions generated from atmospheric or dopant molecules undergo ion-molecule reactions with the sample ...

  7. Atmospheric-pressure chemical ionization - Wikipedia

    en.wikipedia.org/wiki/Atmospheric-pressure...

    Atmospheric pressure chemical ionization chamber cross section. Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry which utilizes gas-phase ion-molecule reactions at atmospheric pressure (10 5 Pa), [1] [2] commonly coupled with high-performance liquid chromatography (HPLC). [3]

  8. Chemical ionization - Wikipedia

    en.wikipedia.org/wiki/Chemical_ionization

    Peroxynitrate chemical ionization mass spectrometer at the US National Oceanic and Atmospheric Administration. CI mass spectrometry is a useful tool in structure elucidation of organic compounds. [3] This is possible with CI, because formation of [M+1] + eliminates a stable molecule, which can be used to guess the functional groups present. [3]

  9. Mass spectral interpretation - Wikipedia

    en.wikipedia.org/wiki/Mass_spectral_interpretation

    [1] [2] Mass spectra is a plot of relative abundance against mass-to-charge ratio. It is commonly used for the identification of organic compounds from electron ionization mass spectrometry. [3] [4] Organic chemists obtain mass spectra of chemical compounds as part of structure elucidation and the analysis is part of many organic chemistry ...