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Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
Naltrexone has been shown to decrease the quantity and frequency of ethanol consumption by reducing the dopamine release from the brain after consuming alcohol. [19] [20] [21] It does not appear to change the percentage of people drinking. [22] Its overall benefit has been described as "modest". [23] [19] [24] [25]
Over three to twelve months it increases the number of people who do not drink at all and the number of days without alcohol. [5] It appears to work as well as naltrexone for maintenance of abstinence from alcohol, [ 15 ] however naltrexone works slightly better for reducing alcohol cravings and heavy drinking, [ 16 ] and acamprosate tends to ...
How to stop drinking Depending on whether you’re a light or heavy drinker, your strategy around cutting back will be different. “For a light drinker, you don’t really need to taper,” says ...
“The best way to moderate alcohol consumption is to stop drinking for four weeks, and then after this period of abstinence, return to drinking with a specific plan for moderation,” says Dr ...
White also warns that it can be dangerous to quit drinking alcohol on your own if you’ve been drinking heavily for a period of time. “Each year, alcohol withdrawal contributes to about 1,000 ...
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