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Other bacterial ophthalmia neonatorum should be treated by broad-spectrum antibiotics drops and ointment for 2 weeks. Neonatal inclusion conjunctivitis caused by C. trachomatis should be treated with oral erythromycin. [15] Topical therapy is not effective and also does not treat the infection of the nasopharynx. [16] [17] [18]
Erythromycin's elimination half-life ranges between 1.5 and 2.0 hours and is between 5 and 6 hours in patients with end-stage renal disease. Erythromycin levels peak in the serum 4 hours after dosing; ethylsuccinate peaks 0.5–2.5 hours after dosing, but can be delayed if digested with food. [39]
Erythromycin/benzoyl peroxide is a prescription medication. [ 2 ] Side effects include dry skin, stinging, redness, and itchy rash ( urticaria ), [ 2 ] with recommended usage is 2 times per day, once in the morning and once in the evening, or as prescribed by a doctor.
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
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Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
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