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Desloratadine is used to treat allergic rhinitis, nasal congestion and chronic idiopathic urticaria . [8] It is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness. [8] Desloratadine is available in many dosage forms and under many brand names worldwide. [9]
"Desloratadine and pseudoephedrine combination therapy as a comprehensive treatment for allergic rhinitis and nasal congestion". Expert Opin Drug Metab Toxicol . 5 (6): 683–94.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
Dr. Reddy's Announces the Launch of Desloratadine ODT (Orally Disintegrating Tablets) HYDERABAD, India--(BUSINESS WIRE)-- Dr. Reddy's Laboratories (NYS: RDY) announced today that it has launched ...
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.
Loratadine, another non-sedating antihistamine, is the prodrug of desloratadine, which is largely responsible for the antihistaminergic effects of the parent compound. However, in this case the parent compound does not have the side effects associated with terfenadine, and so both loratadine and its active metabolite , desloratadine, are ...
Bilastine has an effectiveness similar to cetirizine, fexofenadine, and desloratadine. [8] Bilastine was discovered by the Spanish firm FAES Farma [9] and received its first approval in the European Union in 2010 for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. [10] It is also approved in Canada and Australia.
Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H 1 receptor antagonist activity. It further blocks the receptors of the platelet-activating factor (PAF) according to in vitro and in vivo studies.