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Adenovirus infection is a contagious viral disease, caused by adenoviruses, commonly resulting in a respiratory tract infection. [ 1 ] [ 9 ] Typical symptoms range from those of a common cold , such as nasal congestion , rhinitis , and cough , to difficulty breathing as in pneumonia . [ 9 ]
Human adenovirus 36 (HAdV-36) or Ad-36 or Adv36 is one of 52 types of adenoviruses known to infect humans. AD-36, first isolated in 1978 from the feces of a girl suffering from diabetes and enteritis, [ 1 ] has long been recognized as a cause of respiratory and eye infections in humans. [ 2 ]
An adenovirus vaccine is a vaccine against adenovirus infection. [3] According to American CDC, "There is currently no adenovirus vaccine available to the general public. [4] It should not be confused with the strategy of using adenovirus as a viral vector to develop vaccines for other pathogens, or as a general gene carrier. [5] [6] [7]
In China, oncolytic adenovirus is an approved cancer treatment. [46] Specific modifications on fiber proteins are used to target Adenovirus to certain cell types; [47] a major effort is made to limit hepatotoxicity and prevent multiple organ failure.
Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by adenoviruses. [1] It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. [3]
Human adenovirus 41 (HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. [ 1 ] It can particularly target the gastrointestinal tract to cause gastroenteritis , with symptoms similar to rotavirus gastroenteritis and norovirus . [ 2 ]
The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx.
In some cases, the adenovirus will insert the new gene into a cell. If the treatment is successful, the new gene will make a functional protein to treat a disease. In order to replicate, viruses introduce their genetic material into the host cell, tricking the host's cellular machinery into using it as blueprints for viral proteins.