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Gemcitabine is in the nucleoside analog family of medication. [3] It works by blocking the creation of new DNA, which results in cell death. [3] Gemcitabine was patented in 1983 and was approved for medical use in 1995. [7] Generic versions were introduced in Europe in 2009 and in the US in 2010. [8] [9] It is on the WHO Model List of Essential ...
There is a large family of nucleoside analogue reverse transcriptase inhibitors, because DNA production by reverse transcriptase is very different from normal human DNA replication, so it is possible to design nucleoside analogues that are preferentially incorporated by the former. Some nucleoside analogues, however, can function both as NRTIs ...
GVD is a chemotherapy regimen, used for salvage treatment of relapsed or refractory Hodgkin disease, including those patients who relapse after stem cell transplantation. [1]
A full alphabetical listing is included after the categorical listing. The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide , doxorubicin , vincristine and prednisone .
Azacitidine is a chemical analogue of the nucleoside cytidine, which is present in DNA and RNA.It is thought to have antineoplastic activity via two mechanisms – at low doses, by inhibiting of DNA methyltransferase, causing hypomethylation of DNA, [16] and at high doses, by its direct cytotoxicity to abnormal hematopoietic cells in the bone marrow through its incorporation into DNA and RNA ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
According to another study, when measured in a different solution, the DNA chain measured 22–26 Å (2.2–2.6 nm) wide, and one nucleotide unit measured 3.3 Å (0.33 nm) long. [10] The buoyant density of most DNA is 1.7g/cm 3. [11] DNA does not usually exist as a single strand, but instead as a pair of strands that are held tightly together.
Radiolab ' s first nine seasons (February 2002–April 2011) comprised five episodes each. Subsequent seasons contained between nine and ten episodes. [2] [3] Season 15 began airing in January 2017. In 2018, the show's seasonal and episode format became obscured when online content moved from radiolab.org to ‘wnycstudios.org’.