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The most obvious symptom of alcohol flush reaction is flushing on a person's face and body after drinking alcohol. [4] Other effects include "nausea, headache and general physical discomfort". [ 9 ] People affected by this condition show greater reduction in psychomotor functions on alcohol consumption than those without.
Alcohol withdrawal syndrome (AWS) is a set of symptoms that can occur following a reduction in or cessation of alcohol use after a period of excessive use. [1] Symptoms typically include anxiety , shakiness , sweating, vomiting, fast heart rate , and a mild fever. [ 1 ]
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
Alcohol is a potent neurotoxin. [5] The National Institute on Alcohol Abuse and Alcoholism has found, "Alcoholism may accelerate normal aging or cause premature aging of the brain." [6] Another report by the same agency found, "Chronic alcohol consumption, as well as chronic glucocorticoid exposure, can result in premature and/or exaggerated ...
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Skin flushing and nasal congestion are the most common symptoms of intolerance after alcohol ingestion. [ 5 ] [ 6 ] It may also be characterized as intolerance causing hangover symptoms similar to the "disulfiram-like reaction" of aldehyde dehydrogenase deficiency or chronic fatigue syndrome .