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Fasting prior to glucose testing may be required with some test types. Fasting blood sugar test, for example, requires 10–16 hour-long period of not eating before the test. [1] Blood sugar levels can be affected by some drugs and prior to some glucose tests these medications should be temporarily given up or their dosages should be decreased.
But following meals, capillary and arterial blood glucose levels can be significantly higher than venous levels. Although these differences vary widely, one study found that following the consumption of 50 grams of glucose, "the mean capillary blood glucose concentration is higher than the mean venous blood glucose concentration by 35%." [33] [34]
The disadvantage of this method was that the test strip had to be developed after a precise interval (the blood had to be washed away), and the meter needed to be calibrated frequently. Most glucometers today use an electrochemical method. Test strips contain a capillary that sucks up a reproducible amount of blood. The glucose in the blood ...
The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
The test employs the Trinder reagent, and is a colour change test resulting from the Trinder reaction. The Trinder reagent, named after P. Trinder of the Biochemistry Department of the Royal Infirmary in Sunderland (see the article listed in further reading ), comprises an aminoantipyrine (such as 4-aminoantipyrine ) and phenol (p-hydroxybenzene).
Hyperglycemic clamp technique: The plasma glucose concentration is acutely raised to 125 mg/dl above basal levels by a continuous infusion of glucose. This hyperglycemic plateau is maintained by adjustment of a variable glucose infusion, based on the rate of insulin secretion and glucose metabolism. Because the plasma glucose concentration is ...
Blood glucose monitoring is the use of a glucose meter for testing the concentration of glucose in the blood . Particularly important in diabetes management , a blood glucose test is typically performed by piercing the skin (typically, via fingerstick ) to draw blood, then applying the blood to a chemically active disposable 'test-strip'.
Substance in water + 3 mL Benedict's solution, then boil for few minutes and allow to cool. Red, green, or yellow precipitate is obtained Reducing sugar, such as glucose, is present Substance in water + 3 mL Benedict's solution, then boil for few minutes and allow to cool. Solution remains clear or is a little blue Reducing sugar is not present