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Lenacapavir, sold under the brand name Sunlenca, is an antiretroviral medication used to treat HIV/AIDS. [9] [10] It is taken by mouth or by subcutaneous injection.[9] [10]The most common side effects include reactions at the injection site and nausea.
In 2021, Viatris was ranked 5th by Fortune on its annual "Change the World" list for having "transformed the treatment of HIV around the world in the [previous] five years through the first low-cost antiretroviral drug for first-line treatment of HIV and a children's version in the form of fruit-flavored tablets that dissolve in liquid. [10]
This is a timeline of HIV/AIDS, including but not limited to cases before 1980. Pre-1980s See also: Timeline of early HIV/AIDS cases Researchers estimate that some time in the early 20th century, a form of Simian immunodeficiency virus found in chimpanzees (SIVcpz) first entered humans in Central Africa and began circulating in Léopoldville (modern-day Kinshasa) by the 1920s. This gave rise ...
The HTLV-III/LAV virus appears to have been introduced among IV drug users in the late 1970s in New York City." [80] [81] Anna Thompson writes on the website TheBody.com in an article dated Autumn 1993: "Many women were dying in the late '70s of pneumonia, cervical cancer, and other illnesses complicated by 'mysteriously' suppressed immune systems.
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
Heterosexual men or women who do not regularly use condoms during sex with partners of unknown HIV status who are substantial risk; Injection of drugs in the last six months with sharing of equipment; Serodiscordant heterosexual and homosexual partners, where one partner is HIV-positive and the other HIV-negative
Resistance ranged from 3.9% to 8.6% and reached 19.6% among people who have received and transitioned to a dolutegravir-containing antiretroviral therapy (ART) regimen to combat high HIV viral loads.
The drug works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. By interfering with this process, which is central to the replication of HIV, emtricitabine can help to lower the amount of HIV, or " viral load ", in a patient's body and can indirectly increase the number of immune system cells (namely T ...