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BrainMaps is an NIH-funded interactive zoomable high-resolution digital brain atlas and virtual microscope that is based on more than 140 million megapixels (140 terabytes) of scanned images of serial sections of both primate and non-primate brains and that is integrated with a high-speed database for querying and retrieving data about brain ...
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The world record for the spatial resolution of a whole-brain MRI image was a 100-micrometer volume (image) achieved in 2019. The sample acquisition took about 100 hours. [ 2 ] The spatial world record of a whole human brain of any method was an X-ray tomography scan performing at the ESRF (European synchrotron radiation facility), which had a ...
All neuroimaging is considered part of brain mapping. Brain mapping can be conceived as a higher form of neuroimaging, producing brain images supplemented by the result of additional (imaging or non-imaging) data processing or analysis, such as maps projecting (measures of) behavior onto brain regions (see fMRI).
A full electron microscopy (EM) connectome of the larval brain of D. melanogaster, including 3016 neurons and 548,000 synapses, was published in March 2023. [ 89 ] [ 90 ] [ 91 ] For adults, partial EM connectomes of the brain (~120,000 neurons, ~30,000,000 synapses) [ 92 ] [ 93 ] [ 94 ] or the ventral nerve cord (VNC, the fly's equivalent of ...
Brain mapping is further defined as the study of the anatomy and function of the brain and spinal cord through the use of imaging (including intra-operative, microscopic, endoscopic and multi-modality imaging), immunohistochemistry, molecular and optogenetics, stem cell and cellular biology, engineering (material, electrical and biomedical ...
Digital reconstruction or tracing of neuron morphology is a fundamental task in computational neuroscience. [1] [2] [3] It is also critical for mapping neuronal circuits based on advanced microscope images, usually based on light microscopy (e.g. laser scanning microscopy, bright field imaging) or electron microscopy or other methods.
The EyeWire project harnesses human computation in a game to trace neurons through images of a volume of retina obtained using serial block-face scanning electron microscopy. [ 7 ] Many different samples can be prepared for serial block-face scanning electron microscopy and the ultramicrotome is able to cut many materials, therefore this ...