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The main metabolite in urine is the ester of glucuronic acid and 11-OH-THC and free THC-COOH. In the feces, mainly 11-OH-THC was detected. [37] Estimates of the elimination half-life of THC are variable. [23] THC was reported to have a fast initial half-life of 6 minutes and a long terminal half-life of 22 hours in a population pharmacokinetic ...
Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9-THC), the compound commonly known as THC, with which it co-occurs in hemp; natural quantities of ∆ 8-THC found in hemp are low.
Dronabinol is the INN for delta-9-THC [157] [158] (there is a common confusion according to which the word "dronabinol" would only refer to synthetic delta-9-THC, which is incorrect [159]). Cannabidiol is also the official INN for the molecule, granted in 2017. [160] Nabilone is the INN for a synthetic cannabinoid analog (not present in ...
Because the law limited only Δ 9-THC levels, many other cannabinoids are generally considered legal to sell and are widely available in stores and online, including Δ 8-THC, Δ 10-THC, HHC, and THCP, [68] [69] but have not had the same in-depth research that the Δ 9 isomer has on the human body; carrying potential risks in the short- or long ...
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
Δ 9-Tetrahydrocannabutol (tetrahydrocannabinol-C4, THC-C4, Δ 9-THCB, (C4)-Δ 9-THC, butyl-THC) is a phytocannabinoid found in cannabis that is a homologue of tetrahydrocannabinol (THC), the main active component of Cannabis. [1] Structurally, they are only different by the pentyl side chain being replaced by a butyl side chain.
THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term THC-O-acetate and its variations are commonly used for two types of the substance, dependent on which cannabinoid it is synthesized from. The difference between Δ 8-THC and Δ 9-THC is bond placement on the cyclohexene ring. [1]
THC hemisuccinate (Δ 9-THC-O-hemisuccinate, Dronabinol hemisuccinate) is a synthetic derivative of tetrahydrocannabinol, developed in the 1990s. It is a water-soluble prodrug ester which is converted into THC inside the body, and was developed to overcome the poor bioavailability of THC when taken by non-inhaled routes of administration .