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An uncommon but significant complication of dextran osmotic effect is acute kidney injury. [15] The pathogenesis of this kidney failure is the subject of many debates with direct toxic effect on tubules and glomerulus versus intraluminal hyperviscosity being some of the proposed mechanisms.
Dextran has yet to be approved for any clinical uses in drug delivery due to a wide variety of limitations including heterogeneity, undesirable side effects, and unknown biological pathways. Changes in the molecular weight of dextran have been shown to alter biological activity, indicating a need for separation and purification processes to ...
Dextran sulphate sodium (DSS), or dextran sodium sulphate (or any of the former with "sulfate") is a synthetic sulphated polysaccharide with anticoagulant activity used in immunological research to induce colitis. [1] [2] Dextran polymer molecules with a molecular weight of 36–50 kDa are frequently used to this end. [2]
Dextran 70 is a type of fluid given by injection into a vein to expand blood volume. [1] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. [2] However, it does not carry oxygen. [2] Common side effects include vomiting, fever, and joint pains. [2]
In this process, a ligand is immobilized on the dextran surface of the SPR crystal. Through a microflow system, a solution with the analyte is injected over the ligand-covered surface. The binding of the analyte to the ligand causes an increase in the SPR signal (expressed in response units, RU).
1. Your sense of humor is so sharp it should come with a warning label 2. You understand me better than anyone else—including myself! 3. You have the organizational skills of a superhero who is ...
Insulin is a hormone that helps move sugar from your blood into your cells. When your body doesn’t respond as well to insulin, it’s called insulin resistance.Insulin resistance can lead to ...
Nevertheless, attempts to use β-Cyclodextrin for the prevention of atherosclerosis, [31] age-related lipofuscin accumulation [32] and obesity encounter an obstacle in the form of damage to the auditory nerve [33] and nephrotoxic effect.