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It was the original prototype from which most methods of treatment are derived. It is also the least expensive, best tested and safest of all available drugs. The emergence of drug-resistant parasitic strains is rapidly decreasing its effectiveness; however, it is still the first-line drug of choice in most sub-Saharan African countries. It is ...
Artesunate is the first-line treatment for children or adults with severe malaria, [16] [17] [18] usually in combination with another antimalarial drug. There is moderate-quality evidence that treatment with artesunate plus mefloquine is superior to treatment with artesunate plus amodiaquine or artesunate plus sulfadoxine-pyrimethamine. [19]
ACTs are recommended by the World Health Organization (WHO) as first-line treatment for uncomplicated P. falciparum malaria [10] and, in 2004, the Global Fund to Fight AIDS, Tuberculosis and Malaria, the largest global funding source for malaria control, [11] began reprogramming all approved grants to procure ACTs in areas with high levels of ...
The first treatment identified is thought to be quinine, one of four alkaloids from the bark of the Cinchona tree. Originally it was used by the tribes of Ecuador and Peru for treating fevers. Its role in treating malaria was recognised and recorded first by an Augustine monk from Lima, Peru in 1633. Seven years later the drug had reached ...
Artemisinin (/ ˌ ɑːr t ɪ ˈ m iː s ɪ n ɪ n /) and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum. [1] It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery. [2]
The first effective treatment for malaria came from the bark of the cinchona tree, which contains quinine. After the link to mosquitos and their parasites was identified in the early twentieth century, mosquito control measures such as widespread use of the insecticide DDT , swamp drainage, covering or oiling the surface of open water sources ...
The prospect that malaria drugs will become go-to medications to treat COVID-19 before they've been rigorously tested is prompting safety warnings.
Artemether is a medication used for the treatment of malaria. [1] [2] The injectable form is specifically used for severe malaria rather than quinine. [2] In adults, it may not be as effective as artesunate. [2] It is given by injection in a muscle. [2] It is also available by mouth in combination with lumefantrine, known as artemether ...