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Bacteria in the human gut’s intestines are the most diverse in the human body and play a vital role in human health. In the gastrointestinal tract, dysbiosis manifests particularly during small intestinal bacterial overgrowth (SIBO), commonly caused by a decrease in the passage of food and waste through the gastrointestinal tract following surgery or other pre-existing conditions. [17]
The gut microbiota is important for maintaining homeostasis in the intestine. Development of intestinal cancer is associated with an imbalance in the natural microflora (dysbiosis). [118] The secondary bile acid deoxycholic acid is associated with alterations of the microbial community that lead to increased intestinal carcinogenesis. [118]
The species and diversity of the microorganisms may be related to the various levels of hormones during pregnancy. Vaginal flora can be transmitted to babies during birth. Vaginal dysbiosis can lead to vaginal infections like bacterial vaginosis which makes one relatively susceptible to sexually transmitted diseases.
Some probiotic strains have been shown to have bactericidal and bacteriostatic activity against H. pylori, and also help to balance the gut dysbiosis. [ 155 ] [ 134 ] Antibiotics have a negative impact on gastrointestinal microbiota and cause nausea, diarrhea, and sickness for which probiotics can alleviate.
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
[11] [3] Gut dysbiosis occurs when there is an alteration in the composition of the gut microbiota that leads to a dysfunction and an unhealthy state. [11] An overgrowth of bacteria in the small intestine can metabolize levodopa into dopamine, preventing it from reaching the brain. [17]
Researchers compared the microbiomes of the mouth and gut in 200 participants who had had a stroke within the past seven days (test group) with the microbiomes of 50 individuals without a history ...
The gut microbiota are very important for the host health because they play role in degradation of non-digestible polysaccharides (fermentation of resistant starch, oligosaccharides, inulin) strengthening gut integrity or shaping the intestinal epithelium, harvesting energy, protecting against pathogens, and regulating host immunity.