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Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
While still in its early phase, a growing number of toy marketers are embracing MESH — or mental, emotional and social health — as a designation for toys that teach kids skills like how to ...
Emotional dysregulation is characterized by an inability to flexibly respond to and manage emotional states, resulting in intense and prolonged emotional reactions that deviate from social norms, given the nature of the environmental stimuli encountered. Such reactions not only deviate from accepted social norms but also surpass what is ...
[3] [4] [6] Food does not significantly influence the extent of absorption of anastrozole. [4] [6] Peak levels of anastrozole occur a median 3 hours after administration, but with a wide range of 2 to 12 hours. [2] [4] Steady-state levels of anastrozole are achieved within 7 to 10 days of continuous administration, with 3.5-fold accumulation.
[5] [6] [7] Through repeated attempts to seek physical and emotional closeness with a caregiver and the responses the child gets, the child develops an internal working model (IWM) that reflects the response of the caregiver to the child. According to Bowlby, attachment provides a secure base from which the child can explore the environment, a ...
Psychosocial short stature (PSS) is a growth disorder that is observed between the ages of 2 and 15, caused by extreme emotional deprivation or stress. The symptoms include decreased growth hormone (GH) and somatomedin secretion, very short stature , weight that is inappropriate for the height, and immature skeletal age .
The PAD emotional state model is a psychological model developed by Albert Mehrabian and James A. Russell (1974 and after) to describe and measure emotional states. PAD uses three numerical dimensions, P leasure, A rousal and D ominance to represent all emotions .