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  2. SOX10 - Wikipedia

    en.wikipedia.org/wiki/SOX10

    20665 Ensembl ENSG00000100146 ENSMUSG00000033006 UniProt P56693 Q04888 RefSeq (mRNA) NM_006941 NM_011437 RefSeq (protein) NP_008872 NP_035567 Location (UCSC) Chr 22: 37.97 – 37.99 Mb Chr 15: 79.04 – 79.05 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. Function This gene encodes a member of the ...

  3. SOX gene family - Wikipedia

    en.wikipedia.org/wiki/SOX_gene_family

    Sox genes are defined as containing the HMG box of a gene involved in sex determination called SRY, which resides on the Y-chromosome. There are 20 SOX genes present in humans and mice, and 8 present in Drosophila. Almost all Sox genes show at least 50% amino acid similarity with the HMG box in Sry.

  4. Oct-4 - Wikipedia

    en.wikipedia.org/wiki/Oct-4

    Oct4 contributes to the rapid cell cycle of ESCs by promoting progression through the G1 phase, specifically through transcriptional inhibition of cyclin-dependent kinase inhibitors such as p21. [28] CRISPR-Cas9 knockout of the gene in human embryonic stem cells demonstrated that Oct-4 is essential for the development after fertilisation. [29]

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  6. SOX6 - Wikipedia

    en.wikipedia.org/wiki/SOX6

    The highlight of the study was that Sox6 is one of the key regulators of renin and prorenin regulation and JG cell expansion during low salt and dehydration in mice. PMID 31760770; DOI: 10.1152/ajprenal.00095.2019

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  9. SOX17 - Wikipedia

    en.wikipedia.org/wiki/SOX17

    The gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, located on Chromosome 8 q11.23. Its gene body is isolated within a CTCF loop domain. [ 6 ] [ 7 ] [ 8 ] Approximately 230 kb upstream of SOX17 it has been identified a tissue specific differentially (hypo-)methylated region (DMR), which consists of SOX17 ...