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  2. Acidosis - Wikipedia

    en.wikipedia.org/wiki/Acidosis

    Acid consumption from poisoning such as methanol ingestion, elevated levels of iron in the blood, and chronically decreased production of bicarbonate may also produce metabolic acidosis. Metabolic acidosis is compensated for in the lungs, as increased exhalation of carbon dioxide promptly shifts the buffering equation to reduce metabolic acid.

  3. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35. [6] Acidemia and acidosis are not mutually exclusive – pH and hydrogen ion concentrations also depend on the coexistence of other acid-base disorders; therefore, pH levels in people with metabolic acidosis can range from low to high.

  4. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1] The pH of the intracellular fluid and the extracellular fluid need to be ...

  5. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Still, the blood values are approximately equal between the arterial and venous sides for most substances, with the exception of acid–base, blood gases and drugs (used in therapeutic drug monitoring (TDM) assays). [6] Arterial levels for drugs are generally higher than venous levels because of extraction while passing through tissues. [6]

  6. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO −3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper metabolic function. [ 1 ] Catalyzed by carbonic anhydrase, carbon dioxide (CO 2 ...

  7. Acid–base disorder - Wikipedia

    en.wikipedia.org/wiki/Acid–base_disorder

    Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus , the normal range differs based on which umbilical vessel is sampled ( umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38 ...

  8. pH - Wikipedia

    en.wikipedia.org/wiki/PH

    Acidosis, defined by blood pH below 7.35, is the most common disorder of acid–base homeostasis and occurs when there is an excess of acid in the body. In contrast, alkalosis is characterized by excessively high blood pH. Blood pH is usually slightly basic, with a pH of 7.365, referred to as physiological pH in biology and medicine.

  9. Diabetic ketoacidosis - Wikipedia

    en.wikipedia.org/wiki/Diabetic_ketoacidosis

    The administration of sodium bicarbonate solution to rapidly improve the acid levels in the blood is controversial. There is little evidence that it improves outcomes beyond standard therapy, and indeed some evidence that while it may improve the acidity of the blood, it may actually worsen acidity inside the body's cells and increase the risk ...