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Ascites (/ ə ˈ s aɪ t i z /; [5] Greek: ἀσκός, romanized: askos, meaning "bag" or "sac" [6]) is the abnormal build-up of fluid in the abdomen. [1] Technically, it is more than 25 ml of fluid in the peritoneal cavity, although volumes greater than one liter may occur. [4]
Production of albumin can be 60–80% lower in advanced cirrhosis than in healthy liver, an effect amplified by dilution (salt and water retention), fluid shifts (following the accumulation of albumin in extracellular space and ascitic fluid), and even post-transcriptional changes to albumin itself. [8]
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [1] Recently, a third form of liver failure known as acute-on-chronic liver failure (ACLF) is increasingly being recognized. [2]
Fluid retention can be a symptom of underlying conditions such as kidney disease, heart failure and liver disease, says Badgett. Certain cancers and cancer treatments can cause edema.
It is classically marked by weight gain due to fluid retention, increased liver size, and raised levels of bilirubin in the blood. [1] The name sinusoidal obstruction syndrome (SOS) is preferred if hepatic veno-occlusive disease happens as a result of chemotherapy or bone marrow transplantation. [1] [2]
These include the brain, heart, lungs, liver, and kidneys. ... , anemia, nerve damage, and fluid retention can arise," says Nagata. "Without treatment, chronic kidney disease can lead to end-stage ...
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