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List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
As unopposed estrogen therapy (using estrogen alone without progesterone) increases the risk of endometrial hyperplasia and endometrial cancer in women with intact uteruses, estradiol is usually combined with a progestogen like progesterone or medroxyprogesterone acetate to prevent the effects of estradiol on the endometrium.
Estriol is well-tolerated and produces relatively few adverse effects. [12] [18] Side effects may include breast tenderness, vaginal discomfort and discharge, and endometrial hyperplasia. [12] [18] Estriol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like ...
In addition to hormones taken as pills, there are patches that can deliver similar effects. Women over 60 experiencing vaginal symptoms also could opt for vaginal creams and suppositories that ...
Women’s estrogen and progesterone levels plummet. (They fluctuate wildly during the two to eight years before menopause, known as perimenopause.) Hormone therapy aims to supplement those levels ...
Experts call vaginal estrogen "the holy grail" for its effectiveness in improving vulvar or vaginal itching and burning, painful sex and recurring UTIs.