Search results
Results From The WOW.Com Content Network
RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. [11] It consists of RNA polymerase II, a subset of general transcription factors , and regulatory proteins known as SRB proteins.
RNA polymerase II (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA . [ 3 ] [ 4 ] In humans, RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized from POLR2C ...
RNA Polymerase II Transcription: the process of transcript elongation facilitated by disassembly of nucleosomes. RNAP from T. aquaticus pictured during elongation. Portions of the enzyme were made transparent so as to make the path of RNA and DNA more clear.
5430 20020 Ensembl ENSG00000284832 ENSG00000181222 ENSMUSG00000005198 UniProt P24928 P08775 RefSeq (mRNA) NM_000937 NM_009089 NM_001291068 RefSeq (protein) NP_000928 NP_001277997 Location (UCSC) Chr 17: 7.48 – 7.51 Mb Chr 11: 69.62 – 69.65 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded ...
The promoter is recognized by RNA polymerase and an associated sigma factor, which in turn are often brought to the promoter DNA by an activator protein's binding to its own DNA binding site nearby. In eukaryotes The process is more complicated, and at least seven different factors are necessary for the binding of an RNA polymerase II to the ...
5441 66491 Ensembl ENSG00000177700 ENSMUSG00000038489 UniProt P62875 P62876 RefSeq (mRNA) NM_021128 NM_025593 RefSeq (protein) NP_066951 NP_079869 Location (UCSC) Chr 11: 0.84 – 0.84 Mb Chr 7: 141.05 – 141.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene ...
The positive transcription elongation factor, P-TEFb, is a multiprotein complex that plays an essential role in the regulation of transcription by RNA polymerase II (Pol II) in eukaryotes. [1] Immediately following initiation Pol II becomes trapped in promoter proximal paused positions on the majority of human genes (Figure 1).
DNA-directed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene. [ 5 ] This gene encodes the fourth-largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes.