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The posterior pituitary is not glandular as is the anterior pituitary. Instead, it is largely a collection of axonal projections from the hypothalamus that terminate behind the anterior pituitary, and serve as a site for the secretion of neurohypophysial hormones ( oxytocin and vasopressin ) directly into the blood. [ 2 ]
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Here, the posterior pituitary is a simple flat sheet of tissue at the base of the brain, and there is no pituitary stalk. Rathke's pouch remains open to the outside, close to the nasal openings. Closely associated with the pouch are three distinct clusters of glandular tissue, corresponding to the intermediate lobe, and the rostral and proximal ...
They may be mistaken for the much more common pituitary adenoma, as well as craniopharyngioma and meningioma. Symptoms from the mass effect of the tumor usually include vision disorders, and less often headaches, hypopituitarism (decreased function of the pituitary gland), fatigue, and decreased libido.
Herring bodies or neurosecretory bodies are structures found in the posterior pituitary. They represent the terminal end of the axons from the hypothalamus , and hormones are temporarily stored in these locations.
Damage to the pituitary stalk blocks the release of antidiuretic hormone, resulting in polydipsia (excessive water intake) and polyuria (excessive urination, central diabetes insipidus). The diameter of the pituitary stalk at the level of optic chiasm is 3.3 mm, and at the pituitary gland insertion site is measured at 1.9 mm. [3]
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The oxytocin and vasopressin that is released at the posterior pituitary gland enters the blood, and cannot re-enter the brain because the blood–brain barrier does not allow oxytocin and vasopressin through, but the oxytocin and vasopressin that is released from dendrites acts within the brain. Oxytocin neurons themselves express oxytocin ...