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There is speculation that the castor oil in the hydroxyprogesterone caproate formulation may not be beneficial for pregnancy. [36] [37] Of note, the above-mentioned NEJM study by Meirs et al. compares the effect of hydroxyprogesterone caproate (with the castor oil component) to castor oil injection as the placebo.
Castor oil. Despite some undesirable side effects, castor oil is used for labor induction. There is no high-quality research proving that ingestion of castor oil results in cervical ripening or induction of labor; there is, however, evidence that taking it causes nausea and diarrhea.
Research on the pain-relieving and infection-preventing effects of castor oil is also limited. ... there are potential side effects of applying castor oil topically, including: Rash. Skin irritation.
Castor oil is a glyceride that is hydrolyzed by pancreatic lipase to ricinoleic acid, which produces laxative action by an unknown mechanism. Properties. Site of action: colon, small intestine (see below) [citation needed] Onset of action: 2–6 hours; Examples: castor oil [3]
Common side effects include abdominal bloating and cramps. [3] A potential exists for electrolyte problems as a result of the diarrhea it produces. [3] No evidence of harm to the fetus has been found when used during pregnancy. [3] It is generally regarded as safe during breastfeeding. [5] It is classified as an osmotic laxative. [6]
It is prepared by reacting 35 moles of ethylene oxide with each mole of castor oil. The resulting product is a mixture (CAS number 61791-12-6): the major component is the material in which the hydroxyl groups of the castor oil triglyceride have been ethoxylated with ethylene oxide to form polyethylene glycol ethers.
It is a weaker laxative than bisacodyl and castor oil. [1] Common side effects of senna glycoside include abdominal cramps. [3] It is not recommended for long-term use, as it may result in poor bowel function or electrolyte problems. [1] While no harm has been found to result from use while breastfeeding, such use is not typically recommended. [1]
Other side-effects can include alterations in the structure of the heart, ... When taken during pregnancy, ... Castor oil solution: Intramuscular injection: