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The signs and symptoms of colorectal cancer depend on the location of the tumor in the bowel, and whether it has spread elsewhere in the body ().The classic warning signs include: worsening constipation, blood in the stool, decrease in stool caliber (thickness), loss of appetite, loss of weight, and nausea or vomiting in someone over 50 years old. [15]
Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [3] [4] Generally it is used together with dietary changes and a statin. [5] Alone, it is less preferred than a statin. [4] It is taken by mouth. [4]
Colon cancer will be diagnosed in approximately 150,000 Americans in 2024. It’s the fourth most diagnosed cancer in the United States and one of the leading causes of cancer deaths, according to ...
Clinical studies have been conducted on the use of statins in dementia, [216] lung cancer, [217] nuclear cataracts, [218] hypertension, [219] [220] and prostate cancer [221] and breast cancer. [222] There is no high quality evidence that statins are useful for pneumonia . [ 223 ]
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It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US). Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
These symptoms may occur over a long time, sometimes for years. [2] IBS can negatively affect quality of life and may result in missed school or work or reduced productivity at work. [13] Disorders such as anxiety, major depression, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are common among people with IBS. [1] [14] [note ...