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Metanephric adenoma (MA) is a rare, benign tumour of the kidney, that can have a microscopic appearance similar to a nephroblastoma (Wilms tumours), [1] or a papillary renal cell carcinoma. It should not be confused with the pathologically unrelated, yet similar sounding, mesonephric adenoma .
Metanephric dysplastic hematoma of the sacral region (MDHSR) has been described by Cozzutto and Lazzaroni-Fossati in 1980, [1] by Posalaki et al. in 1981 [2] and by Cozzutto et al. in 1982. [3] Three additional cases were seen by Finegold.
Nephrogenic adenoma is a benign growth typically found in the urinary bladder. It is thought to result from displacement and implantation of renal tubular cells, as this entity in kidney transplant recipients has been shown to be kidney donor derived. [1] This entity should not be confused with the similar-sounding metanephric adenoma.
Wilms' tumor is a malignant tumor containing metanephric blastema, stromal and epithelial derivatives. Characteristic is the presence of abortive tubules and glomeruli surrounded by a spindled cell stroma. The stroma may include striated muscle, cartilage, bone, fat tissue, and fibrous tissue. Dysfunction is caused when the tumor compresses the ...
Histopathologic types of kidney tumor, with relative incidences and prognoses. Cystic nephroma is seen at bottom right in pie chart. cystic partially differentiated nephroblastoma; cystic standard nephroblastoma (cystic Wilm's tumor) cystic mesoblastic nephroma; cystic renal cell carcinoma; other renal cysts
Congenital mesoblastic nephroma, while rare, is the most common kidney neoplasm diagnosed in the first three months of life and accounts for 3-5% of all childhood renal neoplasms. [ 2 ] [ 3 ] It is generally non-aggressive and amenable to surgical removal, though there is a subtype that is more aggressive and tends to spread to other organs .
Compared to other common types of RCC, PRCC exhibits a relatively lower risk of tumor recurrence and cancer-related death after nephrectomy. [48] Specifically, the cancer-specific survival rate at five years following surgery with PRCC has reached up to 91%, while clear cell RCC and chromophobe RCC were 72% and 88%, respectively. [46]
The morphology axis addresses the microscopic structure of the tumor.. This axis has particular importance because the Systematized Nomenclature of Medicine ("SNOMED") has adopted the ICD-O classification of morphology.