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The chorionic villi are at first small and non-vascular. 13–15 days: trophoblast only [1] Secondary: The villi increase in size and ramify, while the mesoderm grows into them. 16–21 days: trophoblast and mesoderm [1] Tertiary: Branches of the umbilical artery and umbilical vein grow into the mesoderm, and in this way the chorionic villi are ...
Immature chorionic villi are larger and have more central blood vessels; thus, the diffusion distance for gas and nutrient exchange is larger and, therefore, placental function is impaired. Low mag. High mag.
On gross pathology, the presence of chorionic villi (left) is diagnostic of products of conception, whereas decidua (right) is not. The diagnosis is based on clinical presentation, quantitative HCG, ultrasound, and pathologic evaluation. A solid, heterogeneous, echogenic mass has a positive predictive value of 80%, but is present in only a ...
In developmental biology, choriogenesis is the formation of the chorion, an outer membrane of the placenta that eventually forms chorionic villi that allow the transfer of blood and nutrients from mother to fetus. [1]
Placenta with attached fetal membranes (ruptured at the margin at the left in the image), which consists of the chorion (outer layer) and amnion (inner layer).. The part of the chorion that is in contact with the decidua capsularis undergoes atrophy, so that by the fourth month scarcely a trace of the villi is left.
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
Histopathology of a chorionic villus, in a tubal pregnancy. The invasive lineage creates cytotrophoblasts that are essential in the process of implantation and forming a fully functional placenta. An undifferentiated cytotrophoblastic stem cell will differentiate into an extravillous cytotrophoblast intermediate and then into an interstitial ...
They are named after J. Isfred Isidore Hofbauer (1871 [2]-1961), [1] a German-American gynecologist who described the cell type in his book Grundzüge einer Biologie der menschlichen Plazenta, mit besonderer Berücksichtigung der Fragen der fötalen Ernährung (Biology of the Human Placenta with a special emphasis on the question of fetal nourishment).