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Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (), heart, brain, eyes, bones, and other parts of the body.
The most common type, also known as candidemia, candedemia, or systemic candidiasis, is caused by Candida species. Candidemia is also among the most common bloodstream infections of any kind. [ 1 ] Infections by other fungi, including Saccharomyces , Aspergillus (as in aspergillemia, also called invasive aspergillosiis) and Cryptococcus , are ...
Diaper candidiasis: an infection of a child's diaper area [1]: 309 Erosio interdigitalis blastomycetica; Candidal onychomycosis (nail infection) caused by Candida [23] [64] Systemic candidiasis [23] Candidemia, a form of fungemia which may lead to sepsis [23] Invasive candidiasis (disseminated candidiasis) — organ infection by Candida [23]
Some subcutaneous fungal infections can invade into deeper structures, resulting in systemic disease. [3] Candida albicans can live in people without producing symptoms, and is able to cause both mild candidiasis in healthy people and severe invasive candidiasis in those who cannot fight infection themselves. [3] [7]
[5] [6] [7] Systemic infections of the bloodstream and major organs (candidemia or invasive candidiasis), particularly in patients with an impaired immune system (immunocompromised), affect over 90,000 people a year in the US. [8] The genome of several Candida species has been sequenced. [8]
Candida albicans is an opportunistic pathogenic yeast [5] that is a common member of the human gut flora. It can also survive outside the human body. It can also survive outside the human body. [ 6 ] [ 7 ] It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults.