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According to Gilboa et al., patients with localized hippocampal damage can score well on a test if it is based on familiarity. [22] Poreh et al. [23] describe a case study of patient A.D., whose damage to the fornix rendered the hippocampus useless, but spared adjacent cortical areas – a fairly rare injury. When the patient was given a test ...
Knockout studies in Aplysia sea slugs indicated that decreasing CREB function blocks long-term changes in synaptic function, but not short-term ones. [3] Changes in synaptic function (i.e., synaptic plasticity) are required for learning and memory [4] As evidence of this, a line of mice with a targeted disruption of the α and δ isoforms of CREB showed intact short-term memory, but disrupted ...
A hippocampus prosthesis is a type of cognitive prosthesis (a prosthesis implanted into the nervous system in order to improve or replace the function of damaged brain tissue). Prosthetic devices replace normal function of a damaged body part; this can be simply a structural replacement (e.g. reconstructive surgery or glass eye) or a ...
Treatment with the cancer drug restored function in the hippocampus in an Alzheimer’s mouse model. It has long been understood that glucose metabolism in the brain is disrupted by aging and ...
The hippocampus has been implicated as a key structure for spatial memory in humans, and studying behavior in food caching birds and other animals has been extremely influential on this view. [27] [38] Sherry and his colleagues were also able to show that food-caching birds have much larger hippocampus’ than non food-caching birds. Without ...
The veterans with PTSD showed an 8% reduction in their right hippocampal volume. The patients that suffered from child abuse showed a 12% reduction in their mean left hippocampal volume. [59] Several of the studies have also shown that people with PTSD have deficits while performing verbal declarative memory tasks in their hippocampus. [59]
To test this proposal, a group of rats with normal hippocampal neurogenesis (control) were subjected to a placement recognition exercise that required proper hippocampus function to complete. Afterwards a second group of rats (experimental) were subjected to the same exercise but in that trial their neurogenesis in the hippocampus was arrested.
In 2025, the so-called income test limit rises from $22,320 to $23,400. After that, the SSA deducts $1 of benefits for every $2 earned over that income threshold. For those who will reach full ...