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The PSD has been proposed to concentrate and organize neurotransmitter receptors in the synaptic cleft. [1] The PSD also serves as a signaling apparatus. For instance kinases and phosphatases in the PSD are activated and released from the PSD to change the activity of proteins located in the spine or are transported to the nucleus to affect ...
[1] Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. Some neurotransmitters are also stored in large dense core vesicles. [2] The neurotransmitter's effect on the target cell is determined by the receptor it binds to.
Ions can create excitatory or inhibitory potentials due to their unique reversal potentials and the membrane's permeability to each ion. The Nernst equation and Goldman equation can calculate membrane potential differences based on ion concentration, offering predictions into how ions can affect postsynaptic potentials. [3]
Nervous tissue, also called neural tissue, is the main tissue component of the nervous system.The nervous system regulates and controls body functions and activity. It consists of two parts: the central nervous system (CNS) comprising the brain and spinal cord, and the peripheral nervous system (PNS) comprising the branching peripheral nerves.
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
The peripheral nervous system (PNS) is a collective term for the nervous system structures that do not lie within the CNS. [17] The large majority of the axon bundles called nerves are considered to belong to the PNS, even when the cell bodies of the neurons to which they belong reside within the brain or spinal cord.
The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia , which lie outside the brain and the spinal cord . [ 1 ]
The PNS includes motor neurons, mediating voluntary movement; the autonomic nervous system, comprising the sympathetic nervous system and the parasympathetic nervous system and regulating involuntary functions; and the enteric nervous system, a semi-independent part of the nervous system whose function is to control the gastrointestinal system.