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Phosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15% of the phospholipids in the human cerebral cortex. [7] In the plasma membrane, PS is localized exclusively in the cytoplasmic leaflet where it forms part of protein docking sites necessary for the activation of several key signaling pathways.
The major membrane lipids PtdCho - Phosphatidylcholine; PtdEtn - Phosphatidylethanolamine; PtdIns - Phosphatidylinositol; PtdSer - Phosphatidylserine.. Membrane lipids are a group of compounds (structurally similar to fats and oils) which form the lipid bilayer of the cell membrane.
Other names in common use include phosphatidylserine synthase, CDPdiglyceride-serine O-phosphatidyltransferase, PS synthase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol, (CDPdiglyceride):L-serine O-phosphatidyltransferase, phosphatidylserine synthetase, CDP-diacylglycerol-L-serine O-phosphatidyltransferase, cytidine diphosphoglyceride-serine O ...
19210 Ensembl ENSG00000156471 ENSMUSG00000021518 UniProt P48651 Q99LH2 RefSeq (mRNA) NM_014754 NM_001290225 NM_008959 RefSeq (protein) NP_001277154 NP_055569 NP_032985 Location (UCSC) Chr 8: 96.26 – 96.34 Mb Chr 13: 67.08 – 67.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phosphatidylserine synthase 1 is a protein that in humans is encoded by the PTDSS1 gene. Function The ...
Phospholipid arrangement in cell membranes. Phosphatidylcholine is the major component of lecithin.It is also a source for choline in the synthesis of acetylcholine in cholinergic neurons.
A classic example of this is phosphatidylserine-triggered phagocytosis. Normally, phosphatidylserine is asymmetrically distributed in the cell membrane and is present only on the interior side. During programmed cell death a protein called a scramblase equilibrates this distribution, displaying phosphatidylserine on the extracellular bilayer ...
Photosystem II (of cyanobacteria and green plants) is composed of around 20 subunits (depending on the organism) as well as other accessory, light-harvesting proteins. Each photosystem II contains at least 99 cofactors: 35 chlorophyll a, 12 beta-carotene , two pheophytin , two plastoquinone , two heme , one bicarbonate, 20 lipids, the Mn
The enzyme phosphatidylserine decarboxylase (EC 4.1.1.65) catalyzes the chemical reaction phosphatidyl-L-serine ⇌ {\displaystyle \rightleftharpoons } phosphatidylethanolamine + CO 2 This enzyme belongs to the family of lyases , specifically the carboxy-lyases, which cleave carbon-carbon bonds.