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Crystalluria refers to crystals found in the urine when performing a urine test. Crystalluria is considered often as a benign condition and as one of the side effects of sulfonamides and penicillins. The main reason for the identification of urinary crystals is to detect the presence of the relatively few abnormal types that may represent a ...
Struvite crystals in a human urine sample with a pH of 9. Abundant amorphous phosphate crystals, several squamous and non-squamous epithelial cells and a few leukocytes can also be observed. Another image from the same urine sample as with the image on the left.
Crystals can also appear as poorly defined aggregates of granular material, termed amorphous urates or amorphous phosphates (urates form in acid urine while phosphates form in alkaline urine). These are of no clinical significance, but they can interfere with microscopy by obscuring other elements (especially bacteria). [ 125 ]
A large portion of the crystals in a urine sediment will have this type of morphology, as they can grow at any pH and naturally occur in normal urine. Calcium oxalate monohydrate crystals vary in shape, and can be shaped like dumbbells, spindles, ovals, or picket fences, the last of which is most commonly seen due to ethylene glycol poisoning. [12]
Acute uric acid nephropathy is caused by deposition of uric acid crystals within the kidney interstitium and tubules, leading to partial or complete obstruction of collecting ducts, renal pelvis, or ureter. This obstruction is usually bilateral, and patients follow the clinical course of acute kidney failure.
Urine: For cystine crystals, and casts. The most specific test is the cyanide–nitroprusside test; Ultrasound/CT scan to reveal if a stone is present. Genetic analysis to determine which mutation associated with the disease may be present.
In urine cytology, collected urine is examined microscopically. One limitation, however, is the inability to definitively identify low-grade cancer cells and urine cytology is used mostly to identify high-grade tumors. [4] If the test detects atypical or cancerous cells, further tests may be recommended, such as cystoscopy and a CT scan.
Another test, urine microscopy, looks for the presence of red blood cells, white blood cells, or bacteria. Urine culture is deemed positive if it shows a bacterial colony count of greater than or equal to 10 3 colony-forming units per mL of a typical urinary tract organism. Antibiotic sensitivity can also be tested with these cultures, making ...