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  2. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  3. Adverse drug reaction - Wikipedia

    en.wikipedia.org/wiki/Adverse_drug_reaction

    Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.

  4. List of deaths from drug overdose and intoxication - Wikipedia

    en.wikipedia.org/wiki/List_of_deaths_from_drug...

    [7] [8] Drug use and addiction also increased significantly following the invention of the hypodermic syringe in 1853, [9] with overdose being a leading cause of death among intravenous drug users. [10] Efforts to prohibit various drugs began to be enacted in the early 20th century, though the effectiveness of such policies is debated. Deaths ...

  5. Arguments for and against drug prohibition - Wikipedia

    en.wikipedia.org/wiki/Arguments_for_and_against...

    In Europe as of 2007, Sweden spends the second highest percentage of GDP, after the Netherlands, on drug control. [12] The UNODC argues that when Sweden reduced spending on education and rehabilitation in the 1990s in a context of higher youth unemployment and declining GDP growth, illicit drug use rose [13] but restoring expenditure from 2002 again sharply decreased drug use as student ...

  6. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  7. Comedown (drugs) - Wikipedia

    en.wikipedia.org/wiki/Comedown_(drugs)

    Generally, a comedown can happen to anyone as a transient symptom, but in people who are dependent on the drug (especially those addicted to it), it is an early symptom of withdrawal and thus can be followed by others. Various drug classes, most especially stimulants and, to a lesser degree, opioids and sedatives, are subject to comedowns. [2]

  8. Drug - Wikipedia

    en.wikipedia.org/wiki/Drug

    The number of people who benefit from a drug determines if drug trials are worth carrying out, given that phase III trials may cost between $100 million and $700 million per drug. This is the motivation behind personalized medicine , that is, to develop drugs that are adapted to individual patients.

  9. Drug-induced angioedema - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_angioedema

    The chance of drug-induced angioedema is extremely uncommon, however, as studies show incidence of less than 1%. [4] The reason this adverse effect may occur is due to the build-up of bradykinin, a vasodilator. This causes blood vessels to dilate and allow for fluid buildup in the mucosal surfaces.