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Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene. [5]SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage.
This can occur "in vitro" in embryoid bodies (EB) derived from embryonic stem cells; this process in EB is similar to "in vivo" vasculogenesis. Important signaling factors for vasculogenesis are TGF-β , BMP4 , and VEGF , all of which promote pluripotent stem cells to differentiate into mesoderm, endothelial progenitor cells, and then into ...
Since gastrulation is a very rapid process, E-cadherin is repressed transcriptionally by Twist and SNAI1 (commonly called Snail), and at the protein level by P38 interacting protein. The primitive streak, through invagination, further generates mesoendoderm, which separates to form a mesoderm and an endoderm, again through EMT.
The mesodermal induction properties of VegT are dose-dependent, such that in Xenopus animal cap explants, high doses induces dorsal mesoderm, while lower doses result in ventral mesoderm (23). Most importantly, VegT plays a significant role in Xbra expression, and this is dependent on FGF signaling.
The intermediate mesoderm connects the paraxial mesoderm with the lateral plate mesoderm, and differentiates into urogenital structures. [12] In upper thoracic and cervical regions, this forms the nephrotomes. In caudal regions, it forms the nephrogenic cord. It also helps to develop the excretory units of the urinary system and the gonads. [4]
In vitro and in response to specific cocktails of hormones (mainly auxins and cytokinins), most plant tissues can de-differentiate and form a mass of dividing totipotent stem cells called a callus. Organogenesis can then occur from those cells. The type of organ that is formed depends on the relative concentrations of the hormones in the medium.
145873 17293 Ensembl ENSG00000188095 ENSMUSG00000030543 UniProt Q0VG99 O08574 RefSeq (mRNA) NM_001039958 NM_008589 RefSeq (protein) NP_001035047 NP_032615 Location (UCSC) Chr 15: 89.76 – 89.78 Mb Chr 7: 79.46 – 79.46 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein ...
Xbra is a homologue of Brachyury (T) gene for Xenopus. [1] It is a transcription activator involved in vertebrate gastrulation which controls posterior mesoderm patterning and notochord differentiation by activating transcription of genes expressed throughout mesoderm. [2]