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  2. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

  3. GABAA receptor - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor

    The ionotropic GABA A receptor protein complex is also the molecular target of the benzodiazepine class of tranquilizer drugs. Benzodiazepines do not bind to the same receptor site on the protein complex as does the endogenous ligand GABA (whose binding site is located between α- and β-subunits), but bind to distinct benzodiazepine binding sites situated at the interface between the α- and ...

  4. GABA receptor - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor

    The most common GABA receptor SNPs do not correlate with deleterious health effects in many cases, but do in a few. One significant example of a deleterious mutation is the major association between several GABA receptor gene polymorphisms and schizophrenia.

  5. GABAA receptor positive allosteric modulator - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor_positive...

    GABA A PAMs increase the effect of GABA by making the channel open more frequently or for longer periods. However, they have no effect if GABA or another agonist is not present. Unlike GABA A receptor agonists , GABA A PAMs do not bind at the same active site as the γ-aminobutyric acid (GABA) neurotransmitter molecule: they affect the receptor ...

  6. Idiopathic hypersomnia - Wikipedia

    en.wikipedia.org/wiki/Idiopathic_hypersomnia

    Idiopathic hypersomnia (IH) is a neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness (EDS). [1] Idiopathic hypersomnia was first described by Bedrich Roth in 1976, and it can be divided into two forms: polysymptomatic and monosymptomatic.

  7. GABA reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/GABA_reuptake_inhibitor

    [9] [10] [11] The inhibitory neurotransmitter GABA plays a complex role in modulating anxiety and stress, regulating sleep, circadian rhythms, mood, cognition, and perception. Low GABA levels are associated with emotional and behavioral disruptions, including short-term and/or long-term stress, anxiety disorders, and sleep disorders. [12]

  8. Ozempic Butt Isn't The Strangest Side Effect Of The Drug ...

    www.aol.com/ozempic-butt-isnt-strangest-side...

    Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.

  9. Gaboxadol - Wikipedia

    en.wikipedia.org/wiki/Gaboxadol

    It acts on the GABA system, but in a different way from benzodiazepines, Z-Drugs, and barbiturates. Lundbeck states that gaboxadol also increases deep sleep (stage 4). Unlike benzodiazepines, gaboxadol does not demonstrate reinforcement in mice or baboons despite activation of dopaminergic neurons in the ventral tegmental area. [3]