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The most common causes of cord compression are tumors, but abscesses and granulomas (e.g. in tuberculosis) are equally capable of producing the syndrome. Tumors that commonly cause cord compression are lung cancer (non-small cell type), breast cancer, prostate cancer, renal cell carcinoma, thyroid cancer, lymphoma and multiple myeloma.
Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of metastatic spinal cord compression is ...
Once the spinal injury has occurred, one of two things may happen. Firstly, hemorrhaging within the spinal cord may cause compression, which damages the spinal cord even further. Another consequence of myelomalacia is improper circulation of blood to the area damaged, resulting in further damage to the spinal cord. [citation needed]
Spinal cord compression. About three percent of cancer patients experience spinal cord compression, usually from expansion of the vertebral body or pedicle due to metastasis, sometimes involving collapse of the vertebral body. Occasionally compression is caused by nonvertebral metastasis adjacent to the spinal cord.
Compression of the upper spinal cord, multiple sclerosis, transverse myelitis, Behçet's disease, osteogenesis imperfecta In neurology , Lhermitte phenomenon , also called the barber chair phenomenon , is an uncomfortable "electrical" sensation that runs down the back and into the limbs.
It is a neurological disorder related to the spinal cord and nerve roots. [3] The severity of CSM is most commonly associated with factors including age, location and extent of spinal cord compression. Incidence of CSM increases with age, where spinal cord compression is bound to be present people aged 55 or above. [4]
Involvement of the vertebrae may lead to spinal cord compression or kyphosis. Myeloma bone disease is due to the overexpression of receptor activator for nuclear factor κ B ligand by bone marrow stroma. RANKL activates osteoclasts, which resorb bone.
Moderate-to-severe cases can cause radicular pain in the legs caused by nerve root compression. [5] The symptoms are usually exacerbated by upright posture and often, but not always, relieved by lying down. Postural headaches can be related to spontaneous spinal cerebrospinal fluid leaks. [6] However, in many patients, dural ectasia is ...