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The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [14] There is a CSF ...
Lewandowsky coined the term blood–brain barrier in 1900, referring to the hypothesized semipermeable membrane which separated the human central nervous system from the rest of the body's vasculature, and which prevented the entry of certain compounds from entering the brain when injected into the bloodstream. [4]
The brain has a powerful ability to keep out blood containing unidentified elements, thanks to a feature known as the blood-brain barrier. Bioengineers believe that they can finally work around ...
The particles were also able to cross the blood-brain barrier. Earlier this year, a study was the first to link the presence of microplastics to higher rates of mortality in people who had higher ...
The blood-brain barrier is especially important since it protects the brain from harmful substances and infection. Inflammation in people with obesity may result in reductions in their blood-brain ...
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Edwin Goldmann (12 November 1862 – 12 August 1913) was a biomedical researcher and surgeon most famous for his contributions in first characterizing the blood–brain barrier. [ 1 ] Discovery of the blood–brain barrier