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[3] Bromobenzene is used to introduce a phenyl group into other compounds. One method involves its conversion to the Grignard reagent, phenylmagnesium bromide. This reagent can be used, e.g. in the reaction with carbon dioxide to prepare benzoic acid. [4] Other methods involve palladium-catalyzed coupling reactions, such as the Suzuki reaction.
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO.It is the simplest amide derivative of benzoic acid.In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5]
Benzyl bromide is used in organic synthesis for the introduction of the benzyl groups when the less expensive benzyl chloride is insufficiently reactive. [6] [7] Benzylations are often achieved in the presence of catalytic amounts of sodium iodide, which generates the more reactive benzyl iodide in situ. [3]
In the first step, two bromine atoms are added to the methyl group of 4-bromotoluene by free radical bromination to form 4-bromobenzal bromide. In the second step, the dibrominated methyl group is hydrolyzed with calcium carbonate , then steam distilled to collect 4-bromobenzaldehyde.
3-Bromobenzaldehyde [2] 4-Bromobenzaldehyde [3] [4] Structure Molecular formula: C 7 H 5 BrO (BrC 6 H 4 COH) Molar mass: 185.020 g/mol Appearance colorless liquid colorless liquid white solid CAS number [6630-33-7] [3132-99-8] [1122-91-4] Properties Density and phase: 1.585 g/ml, liquid 1.587 g/ml, liquid solid Solubility in water: practically ...
N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution, electrophilic addition, and electrophilic substitution reactions in organic chemistry. NBS can be a convenient source of Br • , the bromine radical.
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Chemical structure of 2-bromophenol. A bromophenol is an organic compound consisting of hydroxyl groups and bromine atoms bonded to a benzene ring. They may be viewed as hydroxyl derivatives of bromobenzene, or as brominated derivatives of phenol.